The most common things that will change in your vehicle are mileage, handling, and the feel of the ride. When you’re modifying your vehicle you have to account for new tolerances. An improperly installed lift kit can make your truck rattle around like a ball in a spray paint can if done poorly.
You will get less mileage. This isn’t the biggest flaw, but it’s just something you will have to accept. Bigger tires, bigger lift, means lower mileage but it’s barely going to be noticeable unless you’re a pro accountant who needs to chart everything.
Handling is last but not least. A properly installed kit will leave you driving fine, but done poorly and you’re going to be annoyed. Lift kits can be removed depending on the way it was installed, it’s going to take some work though.
Something to keep in mind is that it’s harder to sell lifted trucks, because of how often lift kits are improperly installed. So if you’re planning on throwing yours up for sale you might want to remove the kit.